Antibacterial and antioxidant properties of macrocyclic Schiff bases with vanadium (V) complexes
نویسندگان
چکیده
Macrocyclic Schiff bases have been synthesized by the condensation of acetyl acetone with semicarbazide hydrochloride and thiosemicarbazide in presence of methanol. Further, their oxovanadium complexes have been synthesized by using vanadium acetylacetone. The structural assignment of these compounds has been made on the basis of MP, TLC, MW determination, conductivities, elemental analysis and UV, IR and HNMR spectral datas. The synthesized compounds were screened for their in vitro growth inhibiting activity against different strains of bacteria viz., Staphylococcus aureus, Bacillus licheniformis, Escherichia coli and Micrococcus luteus (ATCC) and were compared with the standard antibiotic oflaxocin. Also in-vitro antioxidant activity of all compounds was determined by nitric acid free radical scavanging assay.
منابع مشابه
Synthesis and spectral characterization of Macrocyclic Schiff bases with Vanadium(V) complexes and their antibacterial activities
Macrocyclic Schiff base ligands (HDAA) and (EDAA) have been synthesized by condensation of Hydrazinedihydrochloride and Ethylenediamine with acetyl acetone respectively in 1:1 molar ratio in ethanolic solution. Further the vanadium complexes were synthesized by refluxing ligands with [VO(acac)2] in1:1 molar ratio in ethanolic medium. The microanalytical analysis have been obtained and UV, IR, H...
متن کاملAntioxidant Activity and Electrochemical Properties of Tetradentate Schiff Bases and Their Cd(II) Complexes
This study describes the effects of the substituents on electrochemical behavior and antioxidant activity of the three tetradentate Schiff bases, containing ethane-1,2- diamine, propane-1,3- diamine and butan-1,4- diamine as the amine part and salicylaldehyde, and corresponding Cd(II) complexes. Cyclic voltammograms of these compounds were recorded in dimethylsulfoxide and 0.1 M sodium perchlor...
متن کاملSynthesis, Characterization, and Theoretical Studies of the New Antibacterial Zn(II) Complexes from New Fluorescent Schiff Bases Prepared by imidazo[4',5':3,4]benzo[1,2-c]isoxazole
The novel fluorescentheterocyclic bidentate ligands have been synthesized by the high yields reaction of 8-(4-chlorophenyl)-3-Iso-butyl-3H-imidazo[4',5':3,4]benzo[1,2-c]isoxazol-5-amine with p-hydroxybenzaldehyde and p-chlorobenzaldehyde. The ligands reacted with Zn(II) ion to gained novel complexes. The optical properties of these structures were checked and the outcomes represented that t...
متن کاملSynthesis, Antioxidant and Biocidal Features of Macrocyclic Schiff Bases with Oxoanadium (V) Complexes
ABTRACT The macrocyclic ligands are synthesized by taking etylenediamine and semicarbazide hydrochloride with acetyl acetone respectively in ethanolic medium further their Oxovanadium complexes were synthesized by taking metal salt of type VO (acac)2. Ligands and complexes have been analysed for their physical properties with the help of melting point, molecular weight, conductance , TLC determ...
متن کاملBidentate Isatin Schiff Base Ligands Oxovanadium (IV) Complexes
The aim of the present study is to synthesize the oxovanadium complex of the V3+ ion with isatin sciff bases. Spectroscopic methods have been used to confirm these models of complexation and to understand the structures of the species formed in methanolic solution. We also have isolated a complex of Vanadium (III) with isatin schiff bases in the solid phase.
متن کامل